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Practical protocols typically employ 12-16 week cycles aligned with focused body composition phases, followed by maintenance periods or off-cycles

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These protocols cover both intranasal and subcutaneous administration routes

Cohen's newer venture, the precision-medicine biotech MENTSH Therapeutics, carries the work forward, and in April 2025 he joined the scientific advisory board of Niagen Bioscience (the NAD+ company formerly known as ChromaDex), whose CEO Rob Fried described the appointment as a chance to "learn from one of the great minds in mitochondrial and longevity research."14 The lesson for buyers: promising biology and a durable product are different things, and the gap between them is where a lot of money and hope get lost